A-Meb Tablet

• Mebeverine Hydrochloride
• 135 mg
• ACME Laboratories Ltd.
• Unit Price: ৳ 6.01 (50’s pack: ৳ 300.50)

Indications

For the symptomatic treatment of Irritable Bowel Syndrome (IBS) and other conditions include:

• Chronic irritable colon
• Spastic constipation
• Mucous colitis
• Colicky abdominal pain
• Persistent non-specific diarrhea

Therapeutic Class

Anticholinergics

Pharmacology

Mebeverine is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating Irritable Bowel Syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.

Dosage & Administration

For adults, elderly and children over 10 years:

• Mebeverine Tablet: 1 tablet 03 times daily.
• Mebeverine 200 SR Capsule: 1 capsule 02 times daily.

This is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.

Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.

Interaction

Not known.

Contraindications

Not known.

Side Effects

Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.

Pregnancy & Lactation

No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Mebeverine does not excrete in the breast milk after administering the therapeutic dose.

Precautions & Warnings

Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.

Use in Special Populations

Use in children: Mebeverine is not recommended in children under 10 years.

Overdose Effects

On theoretical grounds it may be predicted that CNS excitability will occur in case of overdose. No specific antidote is known gastric lavage and symptomatic treatment is recommended

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.